The specific issue is that, under the 11th Amendment to the Constitution, state governments are given “sovereign immunity” from most legal issues in federal court. And, when it comes to things like patents, the Supreme Court decided that Congress could not pass a law that takes away such sovereign immunity from the states.
In practice, this means state governments — including things like research universities — are able to infringe on patents in the public interest, claiming sovereign immunity in state courts against such claims. We’ve pointed out in the past how hypocritical it is that state universities frequently use such sovereign immunity claims to avoid lawsuits, while at the same time being some of the most aggressive patent trolls in going after others (with the University of California being a prime example). However, it is the law of the land and in the Constitution that sovereign immunity on things like patents cannot be abridged.
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